BCPS Non-clinical Practice Test 2026 - Free BCPS Practice Questions and Study Guide

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For CrCl calculation, which weight is used when BMI is greater than 25?

Actual body weight

Ideal body weight

Adjusted body weight

When estimating creatinine clearance with Cockcroft-Gault, the weight you plug in should reflect metabolically active tissue. If BMI is greater than 25, use adjusted body weight rather than actual body weight because excess fat does not contribute to creatinine production. This approach prevents overestimating renal function in obese patients.

The common adjustment is ABW = IBW + 0.4 × (Actual body weight − IBW). For example, if ideal body weight is 70 kg and actual weight is 90 kg, ABW ≈ 70 + 0.4 × 20 = 78 kg.

Lean body weight